tanespimycin

an aminoquinone macrocyclic compound; shares the ability of geldanamycin to bind to heat shock protein 90 and GRP94; IPI-504 is the hydroquinone chloride salt which is more water soluble; structure in first source

Also Known As:

17AAG; 17- (allylamino)- 17- demethoxy- geldanamycin; 17- (allylamino)- 17- demethoxygeldanamycin; 17-AAG; 17- N- allylamino- 17- demethoxygeldanamycin; 17-allyl-aminogeldanamycin; 17-allylamino-17-demethoxygeldanamycin; 17-allylamino-17-demethoxygeldanamycin hydroquinone; 17-allylamino-17-demethoxygeldanamycin hydroquinone salt; 17-allylamino-geldanamycin; 17-allylaminogeldanamycin; CNF1010; IPI 493; IPI 504; IPI-493; IPI-504; IPI493; IPI504; NSC 330507; NSC-330507; retaspimycin hydrochloride; ((4E,6E,8S,9S,10E,12S,13R,14S,16R)- 13- hydroxy- 8,14- dimethoxy- 4,10,12,16- tetramethyl- 3,20,22- trioxo- 19- (prop- 2- enylamino)- 2- azabicyclo(16.3.1)docosa- 4,6,10,18,21- pentaen- 9- yl) carbamate

Organic Chemicals: 140
- Amides: 2487
  - Lactams: 2278
    - Macrocyclic Lactams: 28
      - tanespimycin: 583
- Quinones: 443
  - Benzoquinones: 25
    - tanespimycin: 583
Polycyclic Compounds: 7
- Macrocyclic Compounds: 16
  - Macrocyclic Lactams: 28
    - tanespimycin: 583

Jian T Che Selected Research

Jian T Che Research Topics

Disease

Drug/Important Bio-Agent (IBA)